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Review Article
Neonatology (Perinatology)
Treatment of congenital cytomegalovirus infection
Gyu Hong Shim
Clin Exp Pediatr. 2023;66(9):384-394.   Published online December 28, 2022
· Congenital cytomegalovirus (CMV) infection is among the most common causes of nongenetic sensorineural hearing loss.
· Congenital CMV is initially treated with intravenous ganciclovir for 2–6 weeks and switched to oral valganciclovir, or with oral valganciclovir for the entire 6-month period.
· Infants with congenital CMV require periodic monitoring of absolute neutrophil count, platelet count, and blood urea nitrogen, creatinine, liver function tests, audiological, ophthalmological, and developmental tests during antiviral medication.
Editorial
Neonatology (Perinatology)
Does cord blood cortisol have a mediating effect on maternal prepregnancy body mass index and birth weight?
Gyu Hong Shim
Clin Exp Pediatr. 2023;66(1):24-25.   Published online November 30, 2022
· A high prepregnancy body mass index (pre-BMI) is associated with large for gestational age (LGA) and macrosomia, whereas a low pre-BMI is associated with small for gestational age (SGA) and low birth weight (LBW).
· The identification of the role of the hypothalamus-pituitary-adrenal axis in the effect of pre-BMI and maternal gestational weight gain on birth weight could reduce the frequency of LGA, macrosomia, SGA, or LBW through maternal diet optimization.
Which factors predict outcomes of neonates with hypoxic-ischemic encephalopathy following therapeutic hypothermia?
Gyu Hong Shim
Clin Exp Pediatr. 2021;64(4):169-171.   Published online December 11, 2020
Determining the therapeutic hypothermia and predict long-term prognosis quickly and accurately in infants with moderate to severe hypoxic-ischemic encephalopathy requires a thorough history taking, physical examination, amplitude-integrated electroencephalography, brain magnetic resonance imaging with diffusion-weighted imaging and proton magnetic resonance spectroscopy, heart evaluation (cardiac enzymes, electrocardiography, and echocardiography), and several other biomarkers.
Original Article
Neurology
Prognostic factors of neurological outcomes in late-preterm and term infants with perinatal asphyxia
Sun Young Seo, Gyu Hong Shim, Myoung Jae Chey, Su Jeong You
Clin Exp Pediatr. 2016;59(11):440-445.   Published online November 18, 2016
Purpose

This study aimed to identify prognostic factors of neurological outcomes, including developmental delay, cerebral palsy and epilepsy in late-preterm and term infants with perinatal asphyxia.

Methods

All late-preterm and term infants with perinatal asphyxia or hypoxic-ischemic insults who admitted the neonatal intensive care unit of Inje University Sanggye Paik Hospital between 2006 and 2014 and were followed up for at least 2...

Study on the neurodevelopmental predictors for the results of the Bayley Scales of Infant Development II in high-risk neonates
Mi Kyeong Woo, Dong Wook Kim, Kyoung Huh, Gyu Hong Shim, Myoung Jae Chey
Clin Exp Pediatr. 2009;52(11):1221-1227.   Published online November 15, 2009
Purpose : To identify the risk factors for poor neurodevelopmental outcomes in high-risk neonates. Methods : We studied 94 infants admitted to the neonatal intensive care unit at the Sanggye Paik Hospital between January 2002 and November 2005 and evaluated the follow-up data. The following events were considered as risk factors: ≤32 weeks of gestation, very low birth weight, Apgar scores...
Short-term clinical outcomes of late preterm infants
Ji Youn Na, Narimi Park, Eun Sun Kim, Jin-A Lee, Gyu Hong Shim, Jin-A Lee, Chang Won Choi, Ee-Kyung Kim, Han-Suk Kim, Beyong Il Kim, Jung-Hwan Choi
Clin Exp Pediatr. 2009;52(3):303-309.   Published online March 15, 2009
Purpose : To identify the short-term clinical outcomes of late preterm infants and to test the hypothesis that late preterm infants have more clinical problems during the early postnatal period than term infants. Methods : One hundred late preterm infants [gestational age (GA) 34+0-36+6 weeks] and the same number of term infants (GA 37+0-41+6 weeks) were randomly selected from 289 late...
Clinical characteristics of severe meconium aspiration syndrome
Chang Won Choi, Beyong Il Kim, Hyun Ju Lee, Kyoung Eun Joung, Gyu Hong Shim, In Suk Lim, Jin-A Lee, Ee-Kyung Kim, Han-Suk Kim, Jung-Hwan Choi
Clin Exp Pediatr. 2008;51(7):713-721.   Published online July 15, 2008
Purpose : This study aims to describe the clinical characteristics of severe meconium aspiration syndrome (MAS) which required mechanical ventilation over 48 h and to delineate the progress of respiratory failure and radiographic findings in severe MAS. Methods : Twelve infants admitted to the Neonatal Intensive Care Unit (NICU) of the Seoul National University Bundang Hospital diagnosed with severe MAS from...
Congenital Heart Disease in Jeju : Postnatal Incidence and Clinical Features
Jung Ha Lee, Gyu Hong Shim, Kyung Sue Shin, Jung Yun Hong, Yeoun Woo Kim, Seong Ho Kim, Chung Il Noh
Clin Exp Pediatr. 2004;47(3):294-303.   Published online March 15, 2004
Purpose : This is a retrospective descriptive study to determine the incidence of congenital heart disease(CHD) in Jeju and to estimate the suitability of the Jeju population as the subject for a regional birth cohort study. Methods : All patients with CHD diagnosed by two dimensional echocardiography in Cheju National University Hospital and Halla General Hospital from January 1999 to...
Risk Factors of Nephrocalcinosis in Very Low Birth Weight(VLBW) Infants
Gyu Hong Shim, Jin A Lee, Yun Jung Shin, Ee Kyung Kim, June Dong Park, Beyong Il Kim, Jung Hwan Choi
Clin Exp Pediatr. 2004;47(3):275-281.   Published online March 15, 2004
Purpose : Nephrocalcinosis in very low birth weight(VLBW) infants were known to be caused by a longer duration of furosemide use. However, etiologies, pathogenesis and risk factors remain unclear. Therefore, we examined the incidence and risk factors of nephrocalcinosis in VLBW infants retrospectively. Methods : Inborn babies of birth weights less than 1,500 gm were examined retrospectively. Data were reviewed on...
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